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CpG island methylation is a common finding in colorectal cancer cell lines.
Tumour cell lines are commonly used in colorectal cancer (CRC) research, including studies designed to assess methylation defects. Although many of the known ...
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Generation of Stable Expression Mammalian Cell Lines Using Lentivirus.
Lentiviruses are used very widely to generate stable expression mammalian cell lines. They are used for both gene down-regulation (by using shRNA) or for gene ...
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Glutathione S-transferase isoenzymes in human tumours and tumour derived cell lines.
An increasing body of evidence indicates that glutathione S-transferases play a role in the intrinsic and acquired resistance of tumours to anticancer drugs. ...
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Cancer Cells Can Exhibit a Sparing FLASH Effect at Low Doses Under Normoxic In Vitro-Conditions.
Background: Irradiation with ultra-high dose rate (FLASH) has been shown to spare normal tissue without hampering tumor control in several in vivo studies. Few ...
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Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines.
A comprehensive analysis of the TP53 gene and its protein status was carried out on a panel of 56 colorectal cancer cell lines. This analysis was based on a ...