Clinical Radiotherapy Core

Frank Van den Heuvel, Academic Lead

The Clinical Radiotherapy Core supports the implementation of clinical trials involving novel applications of radiotherapy or novel radiotherapy techniques including proton beam.

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Research Summary

The Clinical Radiotherapy core sits at the interface of the CRUK/MRC Oxford Institute for Radiation Oncology and the NHS radiotherapy department under the leadership of Professor Frank van den Heuvel, the Head of the NHS Radiotherapy Physics department.

The team works closely with the Radiation Oncology Group and associated staff funded by both University and NHS to support the development and implementation of the Institute’s clinical trials and those of the national trial portfolio (NIHR Clinical Research Network).

The core is increasingly focusing on proton beam therapy, undertaking comparative planning studies of photons and protons to identify subsets of patients where proton therapy has clear cut advantages as a basis for clinical trials in these areas.



Frank Van den Heuvel is an Associate Professor, specialised in medical physics, with specific interests in in-treatment imaging and dose assessment.


A closed parameterization of DNA-damage by charged particles, as a function of energy - a geometrical approach. Van den Heuvel F. PLoS One. 2014 Oct 23; 9(10): e110333

Associated Researchers



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