Site-specific generation of Herceptin radioimmunoconjugates and their in vivo evaluation by PET


Dr Cristina Marculescu, University of Oxford

Date & Time:

Friday, 20 May 2016, 13:30

Old Road Campus Research Building, 71a, b & c, Department of Oncology, Headington OX3 7DQ
CRUK & EPSRC Cancer Imaging Centre in Oxford

A chemoenzymatic approach has been successfully employed to generate various 89Zr-labelled Herceptin conjugates with a high level of purity. The utility of these constructs in an in vivo context was assessed by PET.

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