Reverse the Odds – Cancer Research Needs You!

Dr Anne Kiltie and her team of scientists have created an App in their quest to give patients with bladder cancer the information they need to choose between radiotherapy and surgery.

Virtually every cell in the tumour contains a protein called MRE11, but some tumours contain more of this protein than others.  MRE11 is involved in detecting damage to DNA; the same damage caused by radiotherapy, so being able to tell whether different amounts of MRE11 is important for whether radiotherapy works is the next step in this project.

Anne and her group have developed a simple way of detecting the amount of this protein that each cell contains. We could, therefore, test a patient and tell them something about their tumour and how well radiotherapy would work, although we can’t do this until we’re sure that this will be reliable information.

To make sure their idea works, Anne and her group must test and analyse hundreds of patients’ tumours.  This is where they need your help.  Anne has teamed up with Channel 4 and Cancer Research UK to develop a simple game that allows everyone to help analyse the results of their test for MRE11 and other proteins that might also be important.

By playing the game on the bus or in your coffee break, you can help lend a hand to cancer research.  Every person who plays adds to the analysis and speeds up the process of bringing this technology to the clinic where it can benefit cancer patients.

To find out more visit the Cancer Research UK Blog about ‘Reverse the Odds’.  To get stuck in, download the App to your phone from Amazon, Google Play Store or Apple App Store. The game has been shortlisted for the TIGA games Awards under the ‘Game with a Purpose’ category.

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